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Job Details

Senior Scientist Upstream RNA Process Development

Company name
Pfizer Inc

Pearl River, NY, United States

Employment Type

Sciences, Scientist

Posted on
Apr 10, 2021

Valid Through
Jul 24, 2021

Apply for this job



The Upstream Development group within the Early Bioprocess Development Department in Pfizer Vaccine Research and Development is seeking a Senior Scientist who specializes in molecular biology, with hand on experience and in depth knowledge in generating mRNA using IVT methodologies. Process development expertise is also desirable.


Play a senior role in designing experiments to optimize and enhance mRNA product quality and titer

Develop method for high throughput generation of mRNA material of comparable quality to large scale manufactured material.

Establish monthly work objectives and goals that support the overall program objectives

Perform Design of Experiment (DOE) studies to fully characterize processes.

Present problems and propose solutions in discussions with group members. Offer insights based on experience to group members to help solve existing problems.

Independently analyze experimental data.

Author and review DNA/mRNA methodologies

Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review.

Utilize new technologies and establish those technologies to improve mRNA generation capabilities

Make timely notebook entries and review for completed experiments


PhD in Biochemical Engineering or related discipline with at least 0-2 years of academic, pharmaceutical, or biotechnology experience, or a relevant BS/MS degree with experience appropriate to the position

A strong background in genetics/molecular biology/bioengineering

Hands on experience of running IVT experiments

Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable. Strong verbal and written communication skills are required.


There are no special physical requirements for this role other than the ability to make aseptic transfers. Mental requirements are a detailed understanding of the scientific subject matter, an ability to make scientific judgments and an ability to perform complex data analysis.


The work requires a flexible work schedule to properly perform cell culture and fermentation manipulations. This may involve the necessity of working outside of core hours and on weekends.

Relocation support available

Last Date to Apply: May 28 2020

Eligible for Employee Referral Bonus

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

Company info

Pfizer Inc
Website :

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